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Editorial Board
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| Research Letters with SDA |
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C-terminal residues of Oryza sativa GUN4 are required for the activation of the ChlH subunit of magnesium chelatase in chlorophyll synthesis
03 January 2012
Highlights: ► Oryza sativa GUN4, ChlI, ChlD, and ChlH reconstituted Mg-chelatase activity. ► Preactivation of ChlH with GUN4, protoporphyrin and Mg2+ gave maximum activity. ► Protoporphyrin omission d...
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Shuaixiang Zhou,
Artur Sawicki,
Robert D. Willows,
Meizhong Luo
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205-210
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FLU, a negative feedback regulator of tetrapyrrole biosynthesis, is physically linked to the final steps of the Mg++-branch of this pathway
02 January 2012
Highlights: ► FLU is part of a protein complex bound to chloroplast membranes, primarily on the thylakoids. ► FLU co-migrates on BNGE with several enzymes of the chlorophyll biosynthesis pathway. ► FL...
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Dominika Kauss,
Sylvain Bischof,
Sandro Steiner,
Klaus Apel,
Rasa Meskauskiene
et al.
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211-216
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Activation of macrophage-stimulating protein by human airway trypsin-like protease
12 January 2012
Highlights: ► Human airway trypsin-like protease (HAT) cleaves proMSP at the activating site. ► MSP processed by HAT is biologically active. ► HAT silencing in bronchial epithelial cells reduces phosp...
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Hiroshi Orikawa,
Makiko Kawaguchi,
Takashi Baba,
Kenji Yorita,
Sumio Sakoda,
Hiroaki Kataoka
et al.
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217-221
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| Research Letters |
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Splice blocking of zygotic sox31 leads to developmental arrest shortly after Mid-Blastula Transition and induces apoptosis in zebrafish
29 December 2011
Highlights: ► Splice blocking of sox31 elicits developmental arrest in zebrafish embryos. ► The Sb MO impairs the zygotic gene “up” and maternal mRNA “down” events during MBT. ► The Sb MO of sox31 ind...
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Sheng-Nan Hu,
Hui Yu,
Yun-Bin Zhang,
Zhi-Li Wu,
Yuan-Chang Yan,
Yi-Xue Li,
Yuan-Yuan Li,
Yi-Ping Li
et al.
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222-228
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Human lactoferrin suppresses TNF-α-induced intercellular adhesion molecule-1 expression via competition with NF-κB in endothelial cells
03 January 2012
Highlights: ► Lactoferrin (Lf) inhibits TNF-α-stimulated ICAM-1 expression in endothelial cells. ► Lf down-regulates TNF-α-stimulated ICAM-1 expression at the transcriptional level. ► Lf binds to the ...
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Chan Woo Kim,
Tae Hoon Lee,
Keun Hyung Park,
Sang-Yun Choi,
Jiyoung Kim
et al.
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229-234
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Mitochondria targeting of non-peroxidizable triphenylphosphonium conjugated oleic acid protects mouse embryonic cells against apoptosis: Role of cardiolipin remodeling
29 December 2011
Highlights: ► Generation of non-oxidizable oleate-enriched cardiolipins via mitochondrial targeting. ► Desensitrization to apoptosis via suppression of cardiolipjn oxidation. ► Inhibition of acyl-CoA ...
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Yulia Y. Tyurina,
Muhammad A. Tungekar,
Mi-Yeon Jung,
Vladimir A. Tyurin,
Joel S. Greenberger,
Detcho A. Stoyanovsky,
Valerian E. Kagan
et al.
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235-241
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Chinese hamster AP endonuclease operates by a two-metal ion assisted catalytic mechanism
29 December 2011
Highlights: ► Kinetic evaluation of chAPE1 metal ion specificity. ► Use of inhibitory and activating metal ion to probe for the catalytic mechanism. ► Two metal ion assisted catalysis describes best t...
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Mandula Borjigin,
Pablo Arenaz,
Boguslaw Stec
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242-247
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Functional characterisation of human SGLT-5 as a novel kidney-specific sodium-dependent sugar transporter
02 January 2012
Highlights: ► SGLT are sodium-dependent sugar cotransporters. ► We cloned and functionally characterised a new family member SGLT5. ► We identified SGLT5 as a kidney specific mannose transporter.Abstr...
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Rolf Grempler,
Robert Augustin,
Stefanie Froehner,
Tobias Hildebrandt,
Eric Simon,
Michael Mark,
Peter Eickelmann
et al.
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248-253
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Structural and biochemical insight into glycogenin inactivation by the glycogenosis-causing T82M mutation
04 January 2012
Highlights: ► T82M mutation does not change contacts with UDPG and Tyr194 positioning. ► Autoglucosylation, DBM glucosylation and UDPG hydrolysis are abolished in T82M mutant. ► Glucose transfer activ...
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María E. Carrizo,
Jorge M. Romero,
Federico M. Issoglio,
Juan A. Curtino
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254-257
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Recognition of different DNA sequences by a DNA-binding protein alters protein dynamics differentially
09 January 2012
Highlights: ► Transcription factor CI changes its structure upon DNA-binding. ► Differential protein dynamics upon binding with different DNA sequences. ► Exploration of dynamical time scale associate...
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Tanumoy Mondol,
Subrata Batabyal,
Abhishek Mazumder,
Siddhartha Roy,
Samir Kumar Pal
et al.
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258-262
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VapB as a regulator of osteoclastogenesis via modulation of PLCγ2-Ca2+-NFAT signaling
11 January 2012
Highlights: ► We investigate the role of VapB in RANKL-induced osteoclast differentiation. ► Knock-down of VapB suppressed osteoclastogenesis. ► Over-expression of VapB accelerated RANKL-mediated oste...
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Sik-Won Choi,
Jeong-Tae Yeon,
Kie-In Park,
Chang Hoon Lee,
Byung Soo Youn,
Jaemin Oh,
Myeung Su Lee
et al.
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263-269
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Anti-diabetic and anti-obesity agent sodium tungstate enhances GCN pathway activation through Glc7p inhibition
11 January 2012
Highlights: ► Yeast as a model system for drug mechanism of action. ► Mechanism for anti-diabetic and anti-obesity agent sodium tungstate. ► Tungstate modulates yeast translational control (GCN) pathw...
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C.J. Rodriguez-Hernandez,
J.J. Guinovart,
J.R. Murguia
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270-276
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Mutation of a raft-targeting signal in the transmembrane region retards transport of influenza virus hemagglutinin through the Golgi
11 January 2012
Highlights: ► Hemagglutinin of influenza virus associates with rafts of the plasma membrane. ► A raft-targeting signal in the outer part of the transmembrane region was mutated. ► Processing of HA and...
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Stephanie Engel,
Maren de Vries,
Andreas Herrmann,
Michael Veit
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277-282
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Exploring the mechanism of lipid transfer during biosynthesis of the acidic lipopeptide antibiotic CDA
11 January 2012
Highlights: ► Starter C domain of non-ribosomal peptide synthetases. ► Lipoinitiation reaction of CDA. ► Substrate specificity of the starter C domain Cda-C1. ► In vitro studies of N-acylation of PCP-...
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Femke I. Kraas,
Tobias W. Giessen,
Mohamed A. Marahiel
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283-288
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